Random sample of size 500 from the 4,095 cases in the prevend dataset with all 31 variables.
Format
A tibble with 500 rows and 31 variables:
Casenrcase number, numeric
AgeNumeric, age in years, recorded at time of enrollment.
GenderNumeric vector: 0 = males; 1 = females.
EthnicityNumeric vector: 0 = Western European; 1 = African; 2 = Asian; 3 = Other.
EducationHighest level of education. Numeric: 0 primary school; 1 = lower secondary education; 3 = university.
RFFTNumeric, performance on the Ruff Figural Fluency Test. Scores range from 0 (worst) to 175 (best).
VATNumeric, Visual Association Test score. The VAT is a learning task based on image recognition. Scores may range from 0 (worst) to 12 (best)
CVDHistory of cardiovascular event. Numeric vector: 0 = No; 1 = Yes.
DMDiabetes mellitus (Type 2 diabetes) status at enrollment. Numeric vector: 0 = No; 1 = Yes.
SmokingSmoking status at enrollment. numeric vector: 0 = No; 1 = Yes.
Hypertensionstatus of hypertension at enrollment. Numeric vector: 0 = No; 1 = Yes.
BMINumeric, body mass index, weight divided by height-squared, in kg/m^2
SBPNumeric, systolic blood pressure, in mmHg
DBPNumeric, diastolic blood pressure, in mmHg
MAPNumeric, mean arterial pressure, in mmHg
eGFRNumeric, estimated glomerular filtration rate, a measure of kidney function. Low values indicate possible kidney damage, in mL/min.
Albuminuria.1Albuminuria (mg/24hr) in two categories. Numeric vector: 0 = (< 30); 1 = (\(\ge\) 30)
Albuminuria.2Albuminuria (mg/24hr) in three categories. Numeric: 0 = (0 to < 10), 1 = (10 to < 30); 3 = (\(\ge\) 30).
CholNumeric, total cholesterol, in mmol/L.
HDLNumeric, HDL cholesterol, in mmol/L.
StatinStatin use at enrollment. Numeric vector: 0 = No; 1 = Yes.
SolubilityStatin solubility.Numeric vector: 0 = lipophilic; 1 = hydrophilic; 2 = no statin use. NA indicates statin solubility is missing.
DaysNumeric, total duration of statin use, in days. -1 indicates participant did not use statins
YearsNumeric, total duration of statin use, in years. -1 indicates participant did not use statins.
DDDDefined daily dose of the statin. Numeric vector: From the PLOS One paper, "DDD is defined by the WHO as the drug units representing dosages with approximately similar efficacy. One DDD corresponds to the following dosage for each statin respectively: Simvastatin 30 mg, Pravastatin 30 mg, Fluvastatin 60 mg, Atorvastatin 20 mg and Rosuvastatin 10 mg."
FRSFramingham risk score. Numeric vector. The score, a measure of risk for a cardivascular event within 10 years. Higher values imply increased use. For details see D’Agostino RBS, Vasan RS, Pencina MJ, Wolf PA, Cobain M, et al. (2008) General cardiovascular risk profile for use in primary care: The Framingham Heart Study. Circulation 117: 743–753.
PSPropensity score of statin use. Numeric vector. See the PLOS One paper for the model used to calculate the score
PSquintQuintile of PS. Numeric vector.
GRSIndicator for random sample of 1638 Groningen residents in the study. Numeric vector.
Match_1Numeric, statin users and non-users matched 1:1 on age and educational level. Matched pairs share a common integer label. -1 indicates participant not matched.
Match_2Numeric, statin users and non-users matched 1:1 on Framingham risk score. Matched pairs share a common integer label. -1 indicates participant not matched