Medial temporal lobe (MTL) and other data for 26 participants

The data are from a convenience sample of 25 women and 10 men who were middle-aged or older. The purpose of the study was to understand the relationship between sedentary behavior and thickness of the medial temporal lobe (MTL) in the brain.

Usage

mtl

Format

A data frame with 35 observations on the following 23 variables.

subject: ID for the individual.
sex: Gender, which takes values F (female) or M (male).
ethnic: Ethnicity, simplified to Caucasian and Other.
educ: Years of educational.
e4grp: APOE-4 status, taking a value of E4 or Non-E4.
age: Age, in years.
mmse: Score from the Mini-Mental State Examination, which is a global cognition evaluation.
ham_a: Score on the Hamilton Rating Scale for anxiety.
ham_d: Score on the Hamilton Rating Scale for depression.
dig_sym: We (the authors of this R package) are unsure as to the meaning of this variable.
delay_vp: We (the authors of this R package) are unsure as to the meaning of this variable.
bfr_selective_reminding_delayed: We (the authors of this R package) are unsure as to the meaning of this variable.
sitting: Self-reported time sitting per day, averaged to the nearest hour.
met_minwk: Metabolic equivalent units score (activity level). A score of 0 means "no activity" while 3000 is considered "high activity".
ipa_qgrp: Classification of METminwk into Low or High.
aca1: Thickness of the CA1 subregion of the MTL.
aca23dg: Thickness of the CA23DG subregion of the MTL.
ae_cort: Thickness of a subregion of the MTL.
a_fusi_cort: Thickness of the fusiform gyrus subregion of the MTL.
a_ph_cort: Thickness of the perirhinal cortex subregion of the MTL.
a_pe_cort: Thickness of the entorhinal cortex subregion of the MTL.
asubic: Thickness of the subiculum subregion of the MTL.
total: Total MTL thickness.

Source

Siddarth P, Burggren AC, Eyre HA, Small GW, Merrill DA. 2018. Sedentary behavior associated with reduced medial temporal lobe thickness in middle-aged and older adults. PLoS ONE 13(4): e0195549. doi:10.1371/journal.pone.0195549 .

Thank you to Professor Silas Bergen of Winona State University for pointing us to this dataset!

References

A New York Times article references this study. https://www.nytimes.com/2018/04/19/opinion/standing-up-at-your-desk-could-make-you-smarter.html

Examples


library(ggplot2)

ggplot(mtl, aes(x = ipa_qgrp, y = met_minwk)) +
  geom_boxplot()